Cost and energy saving process for the laboratory-scale production of chloroform-d

Document Type

Article

Publication Date

10-21-2022

Abstract

Deuterochloroform (CDCl3), a commonly deuterated solvent in research and undergraduate laboratories and widely employed for nuclear magnetic resonance analyses, could be prepared using a more sustainable and efficient catalytic process. The synthesis includes a one-pot reaction of hexachloroacetone with deuterium oxide (D2O) in the presence of poly(N-vinylimidazole). The catalyst is more sustainable, highly recyclable, highly chemical and thermally stable, soluble in D2O, and high in efficiency.

Keywords

Sustainable chemistry, Catalysis, Polymer, NMR solvent, One-pot synthesis

Publication Title

Organic Process Research and Development

Divisions

nanocat

Funders

Universiti Malaya, Malaysia (Grant No: ST018- 2022 & RU003-2021)

Volume

26

Issue

11

Publisher

American Chemical Society

Publisher Location

1155 16TH ST, NW, WASHINGTON, DC 20036 USA

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