Cost and energy saving process for the laboratory-scale production of chloroform-d
Document Type
Article
Publication Date
10-21-2022
Abstract
Deuterochloroform (CDCl3), a commonly deuterated solvent in research and undergraduate laboratories and widely employed for nuclear magnetic resonance analyses, could be prepared using a more sustainable and efficient catalytic process. The synthesis includes a one-pot reaction of hexachloroacetone with deuterium oxide (D2O) in the presence of poly(N-vinylimidazole). The catalyst is more sustainable, highly recyclable, highly chemical and thermally stable, soluble in D2O, and high in efficiency.
Keywords
Sustainable chemistry, Catalysis, Polymer, NMR solvent, One-pot synthesis
Divisions
nanocat
Funders
Universiti Malaya, Malaysia (Grant No: ST018- 2022 & RU003-2021)
Publication Title
Organic Process Research and Development
Volume
26
Issue
11
Publisher
American Chemical Society
Publisher Location
1155 16TH ST, NW, WASHINGTON, DC 20036 USA