Nanoantioxidants: The fourth generation of antioxidants-recent research roadmap and future perspectives

Document Type

Article

Publication Date

10-1-2022

Abstract

Antioxidants work by interacting with free radicals and converting them into harmless chemicals, interfering with the progression of potentially hazardous chain reactions. Antioxidants are useful in treating illnesses induced by free radicals because they help minimize oxidative stress. Antioxidants, whether natural or synthetic, have a limited effect on cellular health and function because of their low absorption, inability to traverse cellular membrane, and disintegration during delivery. The benefits of antioxidants, both natural and synthetic, are comparable. The use of antioxidants that are covalently attached to nanoparticles, or encased in particles with a hollow center, or feature the nanomaterial encapsulation of various origins has been employed to solve these challenges to provide improved stability, slow and slow sustained release, biocompatibility, and targeted administration. This review examines the importance of metal-based antioxidants and methods for enhancing antioxidant activities based on recent studies.

Keywords

Nanoantioxidants, DPPH, Nanoparticles

Divisions

Science

Funders

Deanship of Scientific Research at King Khalid University under University of Malaya, Malaysia [IF073-2019] [ST 077-2022]

Publication Title

Coatings

Volume

12

Issue

10

Publisher

MDPI

Publisher Location

ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND

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