Plant-based biosynthesis of copper/copper oxide nanoparticles: An update on their applications in biomedicine, mechanisms, and toxicity
Document Type
Article
Publication Date
4-1-2021
Abstract
Plants are rich in phytoconstituent biomolecules that served as a good source of medicine. More recently, they have been employed in synthesizing metal/metal oxide nanoparticles (NPs) due to their capping and reducing properties. This green synthesis approach is environmentally friendly and allows the production of the desired NPs in different sizes and shapes by manipulating parameters during the synthesis process. The most commonly used metals and oxides are gold (Au), silver (Ag), and copper (Cu). Among these, Cu is a relatively low-cost metal that is more cost-effective than Au and Ag. In this review, we present an overview and current update of plant-mediated Cu/copper oxide (CuO) NPs, including their synthesis, medicinal applications, and mechanisms. Furthermore, the toxic effects of these NPs and their efficacy compared to commercial NPs are reviewed. This review provides an insight into the potential of developing plant-based Cu/CuO NPs as a therapeutic agent for various diseases in the future.
Keywords
Copper, Copper oxide, Green synthesis, Nanoparticles, Biomedicine, Mechanism, Toxicity
Divisions
mechanical,Science,cebar
Funders
Malaysia Ministry of Higher Education-Fundamental Research Grant Scheme (FP027-2019A),Malaysia Ministry of Higher Education-Fundamental Research Grant Scheme (FRGS/1/2019/STG05/UM/02/5)
Publication Title
Biomolecules
Volume
11
Issue
4
Publisher
MDPI
Publisher Location
ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND