Isolation of Streptococcus cuniculi from corneal lesion in laboratory-raised mice
Document Type
Article
Publication Date
2-1-2021
Abstract
Corneal lesions appearing as white mass beneath intact epithelium, with ocular discharge in one mouse, was observed in a batch of laboratory-raised BALB/c mice (n=9 of 56). The affected mice remained active, well-groomed and had normal appetite. Isolates recovered from swab cultures of the external and internal contents of the eye had partial 16S rRNA gene sequence of 99.1% similarity to Streptococcus cuniculi. No previous report of S. cuniculi infection in laboratory rodents has been presented. The isolate was susceptible to all antibiotics tested. We suggest S. cuniculi is an opportunistic bacteria in laboratory mice but are uncertain of its source. Our findings revealed that S. cuniculi is able to colonize laboratory mice and should be considered when mice present with eye lesion or ocular discharge.
Keywords
Eye, Infectious disease, Laboratory mouse, Streptococcus cuniculi
Divisions
tidrec
Funders
Universiti Malaya[RU002-2019],Universiti Malaya[RU005-2020],UMCoE Top 100 Research Grant[UM.00000188/HGA.GV],Pharmaceutical & Nutraceutical R&D Initiatives Fund[09-05-IFN-MEB-005]
Publication Title
Journal of Veterinary Medical Science
Volume
83
Issue
2
Publisher
Japanese Society of Veterinary Science
Publisher Location
UNIV TOKYO, 1-1-1 YAYOI, BUNKYO-KU, TOKYO, 103, JAPAN