Real-time flow impedance evaluation method for ultra-fast early detection of aneurysmal diseases
Document Type
Article
Publication Date
1-1-2021
Abstract
Objective: A novel method to measure the real-time input flow impedance of thoracic aorta aneurysm (TAA) was developed. Methods: The fundamental of real-time input flow impedance was described. The simultaneously measured blood pressure and volumetric flow rate were obtained and used for the calculation. The input flow impedance was then presented in its complexed format: real and imaginary; modulus and phase in the time domain. Results: Unique features of real-time input flow impedance were extracted to correlate with the TAA formation. It showed that the trough of modulus located at the end of each cardiac cycle has different values, which are proportional to the sizes of TAAs. Conclusions: A real-time input flow impedance of the cardiovascular system was presented in this paper. We postulate that the proposed fluid mechanics model has the potential to analyze the pathomechanics of aneurysmal diseases in real-time. © 2020 Elsevier Ltd
Keywords
Aneurysm, Computational fluid dynamics, Input flow impedance
Divisions
fac_eng
Funders
Singapore Ministry of Education Tier 1 Grant (R-397-000-266-114),Singapore Ministry of Health's National Medical Research Council under its Centre Grant (NMRC/CG/M011/2017),Surgery Academic Clinical Program Grant (Biomechanics Lab Programme)
Publication Title
Biomedical Signal Processing and Control
Volume
64
Publisher
Elsevier