Longitudinal assessment of the tiger milk medicinal mushroom, Lignosus rhinocerus (Agaricomycetes), Sclerotium cultivar: Uniformity of bioactive components
Document Type
Article
Publication Date
1-1-2021
Abstract
Traditional use of the tiger milk medicinal mushroom, Lignosus rhinocerus, to treat various illnesses has been recorded for > 4 centuries. Successful cultivation of L. rhinocerus using proprietary solid-state fermentation (SSF) technology by LiGNO Biotech has enabled large-scale production of L. rhinocerus sclerotia (termed L. rhinocerus TM02) and further investigations into its medicinal properties. Pharmacological activities of L. rhinocerus TM02, including its antioxidant, anti-inflammatory, anticancer, and immunomodulatory effects and the bioactive components responsible, have been validated by various scientific studies. In this study, we assessed the consistency of the bioactive components in 11 batches of L. rhinocerus TM02 produced over a 9-year period. The different batches of L. rhinocerus TM02 consisted of stable protein, polysaccharide, and glycoprotein contents, and all tested samples were comparable to the wild type. L. rhinocerus TM02 had greater protein, carbohydrate, and glycoprotein contents, which were mostly bioactive compared to another cultivar from a different cultivation technology (TM-UN). Together with previous scientific validations, L. rhinocerus TM02 produced using SSF cultivation is of optimal quality with high consistent bioactive contents, which can be an appropriate indicator for quality validation of the much sought-after medicinal mushroom, L. rhinocerus.
Keywords
Lignosus rhinocerus, Solid-state fermentation technology, Bioactive components, Consistency, Functional foods, Nutraceuticals, Medicinal mushrooms
Divisions
fac_med
Funders
Universiti Malaya (GPF003B-2020),Universiti Malaya (PV014-2019)
Publication Title
International Journal of Medicinal Mushrooms
Volume
23
Issue
10
Publisher
Begell House Inc
Publisher Location
50 NORTH ST, DANBURY, CT 06810 USA