Effectiveness of medication-assisted therapy in Malaysia. A systematic review and meta-analysis after a decade

Document Type

Article

Publication Date

1-1-2021

Abstract

Background: Medication-assisted therapy especially, Methadone Maintenance Therapy (MMT), has been shown worldwide to have the strength as a treatment option for opioid dependence. Aim: This paper aimed to produce concrete evidence on the effectiveness of MMT in Malaysia. Methods: To systematically review and quantitatively analyse the effectiveness of MMT in Malaysia, the authors searched using main keywords of `effectiveness Methadone in Malaysia' through Google Scholar, EMBASE, PubMed, and Ovid. Results: A total of 41 articles were retrieved from the search and we analysed 16 articles related to the topic. The duplicate title, abstract, and full-text were cleared. Most studies show MMT is effective in improving the quality of life of subjects, reduction in high risk behaviours, improvement of employment rate and it is cost-effective as compared to other options. Conclusions: MMT shows tangible evidence of effectiveness in various aspects including primary and secondary outcomes.

Keywords

Methadone Maintenance Therapy, Opioid dependence, Methadone, Systematic review, Medical Assisted Therapy

Publication Title

Heroin Addiction and Related Clinical Problems

Divisions

fac_med

Funders

University of Malaya under the Wellness Research Centre (WRC) [GC004B-HTM]

Volume

23

Issue

2

Publisher

Pacini Editore

Publisher Location

VIA DELLA GHERARDESCA-ZONA INDUSTRIALE OSPEDALETTO, 56121 PISA, ITALY

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