Diagnostic approaches and contribution of next-generation sequencing technologies in genomic investigation ofVibrio parahaemolyticusthat caused acute hepatopancreatic necrosis disease (AHPND)
Document Type
Article
Publication Date
12-1-2020
Abstract
A unique strain ofVibrio parahaemolyticus(designated as VPAHPND) causes acute hepatopancreatic necrosis disease (AHPND), a deadly bacterial disease associated with mass mortality in cultured shrimps since 2009. AHPND is responsible for severe economic losses worldwide, causing multimillion-dollar loss annually. Because of the rapid and high mortality rates in shrimps, substantial research has been carried out to develop rapid detection techniques. Also, recent technological advances such as the next-generation sequencing (NGS) have made it possible to elucidate relevant information about a pathogen in a single assay. This review summarizes the current research pertaining to VPAHPND, focusing on diagnosis and contribution of NGS technologies in the genomic studies of AHPND.
Keywords
Acute hepatopancreatic necrosis disease, Vibrio parahaemolyticus, Diagnostics, Next-generation sequencing
Divisions
medbio,InstituteofBiologicalSciences,nanocat
Funders
University of Malaya, UM GRANT - Frontier Research Grant [Grant No: UM.0000149/HGA.GV, FG029-17AFR]
Publication Title
Aquaculture International
Volume
28
Issue
6
Publisher
Springer
Publisher Location
VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS