Dietary patterns in childhood and their effect on gut microbiota: An Asian perspective on atopy risk
Document Type
Article
Publication Date
11-1-2020
Abstract
The prevalence of atopic disorders has risen in various parts of the world, including Asia. This increase coincides with rapid urbanization and related lifestyle changes, such as antibiotic overuse, hyperhygienic living conditions, climate change, and air pollution. The transition from a traditional to Westernized diet is known to elicit compositional and functional shifts in gut microbiota, and is thought to underlie the pathogenesis of ‘‘Western-lifestyle’’ diseases in developing societies. A large cohort study involving ethnic minority Asians migrating from Southeast Asia to the United States showed that living in a Westernized environment was associated with loss of gut microbiota diversity, native gut microbiota species, and plant-fiber–degrading functions.1 These changes may be related to loss of intake of staple plant foods that are ubiquitous in a traditional Asian diet or due to an overall paucity of substrate fibers in a Westernized diet.
Keywords
Butyrate, Gut microbiota, Diet, Asian, Allergy
Divisions
paediatrics
Funders
Danone Nutricia
Publication Title
Journal of Allergy and Clinical Immunology
Volume
146
Issue
5
Publisher
Mosby-Elsevier
Publisher Location
360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA