Design, synthesis, characterization, and physical property determination of a new ionic liquid: the preparation of triazolo-pyrimidines at room temperature under metal-free conditions
Document Type
Article
Publication Date
10-1-2020
Abstract
A new ionic liquid is synthesized, and its chemical structure is characterized by FTIR, 1D NMR and 2D NMR, and mass analyses. The thermal behavior and thermal stability of this ionic liquid are investigated. The results approved the formation of 4,4MODIFIER LETTER PRIME-trimethylene-N,NMODIFIER LETTER PRIME-dipiperidinium sulfate instead of 4,4MODIFIER LETTER PRIME-trimethylene-N,NMODIFIER LETTER PRIME-dipiperidinium hydrogen sulfate. Moreover, the synthesis of triazolo-pyrimidine derivatives was successfully conducted in the presence of new ionic liquid at room temperature under metal-free conditions, which demonstrated the catalytic efficiency of this ionic liquid. The workup was carried out without the utilization of high-cost column chromatography. After extraction of desired products, the residual ionic liquid could be recycled and reused in the next runs. New ionic liquid exhibited high catalytic activity even after fifth run with no significant change in the chemical structure.
Keywords
Ionic liquid, Structure elucidation, Heterocycles, Three-component reaction, Waste prevention
Divisions
nanotechnology
Publication Title
Research on Chemical Intermediates
Volume
46
Issue
10
Publisher
Springer Verlag
Publisher Location
VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS