Automated microaneurysms detection and classification using multilevel thresholding and multilayer perceptron
Document Type
Article
Publication Date
4-1-2020
Abstract
The purpose of this paper is to propose an automatic detection of microaneurysms (MAs) in the fundus retina images. In this work, E-optha database of 100 images were utilised to test the performance of the proposed method. The approach covers pre-processing, segmentation, post-processing, feature extraction and classification phases. Methods In pre-processing, the images were filtered and the contrast enhanced. Then, the images were segmented using H-maxima and thresholding technique. Morphological operation was carried out to enhance the images before feature extraction and MAs candidate detection. The detected MAs candidates were classified using multilayer perceptron (MLP). After that, the detected MAs were classified into three classes including background (B), MAs and retinal blood vessels (RBVs). Results The performances of the classifiers were evaluated in terms of accuracy, sensitivity and specificity. The MLP classifier achieved a better performance than the support vector machine with the highest accuracy of 92.28% under condition 2. Conclusion This study demonstrated a methodology for automatic detection of MAs using MLP. The proposed methodology successfully classify the MAs, B and RBVs and was reasonably fast to be implemented in real time.
Keywords
Microaneurysms, Multithresholding, H-maxima, Hybrid filtering
Divisions
fac_eng
Funders
Fundamental Research Grant Scheme (FRGS) [FRGS/1/2015/SKK06/UNIMAP/02/2],Ministry of Education, Malaysia
Publication Title
Journal of Medical and Biological Engineering
Volume
40
Issue
2
Publisher
Springer Verlag (Germany)
Publisher Location
TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY