Spontaneous remission without progression to limbic encephalitis in a patient with LGi1 seropositive faciobrachial dystonic seizure

Document Type

Article

Publication Date

1-1-2016

Abstract

Faciobrachial dystonic seizures are pathognomonic of leucine-rich glioma inactivated-1 (LGi1) antibody, non-paraneoplastic limbic encephalitis. Faciobrachial dystonic seizures usually precede limbic encephalitis by about a month. It is unknown whether, if untreated, faciobrachial dystonic seizures inevitably progress to limbic encephalitis. We present an LGi1 seropositive patient with a year’s history of faciobrachial dystonic seizures, who achieved remission spontaneously without immunotherapy or antiepileptic drug treatment, and did not develop evidence of limbic encephalitis over a three-year follow-up.

Keywords

Brain antibody, Leucine rich glioma inactivated 1 antibody, Levetiracetam, Unclassified drug

Divisions

fac_med

Publication Title

Neurology Asia

Volume

21

Issue

2

Publisher

ASEAN Neurological Association

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