Smart combination of β-cyclodextrin polymer-conjugated magnetic nanosorbent for potential adsorption of deoxyribonucleic acid
Document Type
Article
Publication Date
1-1-2019
Abstract
We reported the synthesis and characterization of Fe 3 O 4 magnetic nanoparticles modified β-cyclodextrin polymer (MNP@βCD-TDI) for the adsorption of deoxyribonucleic acid (DNA). The synthesized MNP@βCD-TDI was characterized by Fourier Transform Infra-Red spectroscopy and Vibrating Sample Magnetometer. Experiments were performed in a batch mode and parameters that affected the DNA adsorption were investigated. An evaluation of the adsorption behavior revealed that Freundlich model and pseudo-second-order fit the equilibrium data. The adsorption efficiency of DNA was found to be at 70 ± 5 % after being recycled three times. This study could be used as a general platform for future work on DNA adsorption and enrichment.
Keywords
β-Cyclodextrin, adsorption, magnetic nanoparticles, biomedical application, inclusion complex
Divisions
CHEMISTRY
Funders
Research University Grant, Universiti Sains Malaysia [RUI: 1001/ CIPPT/811322],Fundamental Research Grant Scheme, Ministry of Higher Education (MOHE), Malaysia [FRGS: 203/CIPPT/6711557]
Publication Title
Separation Science and Technology
Volume
54
Issue
6
Publisher
Taylor & Francis