Lycopodium Alkaloids: Lycoplatyrine A, an Unusual Lycodine–Piperidine Adduct from Lycopodium platyrhizoma and the Absolute Configurations of Lycoplanine D and Lycogladine H
Document Type
Article
Publication Date
1-1-2019
Abstract
Three new Lycopodium alkaloids comprising two lycodine-Type alkaloids (1, 2) and one fawcettimine alkaloid (3), in addition to 16 known alkaloids, were isolated from Lycopodium platyrhizoma. The structures of these alkaloids were elucidated based on analysis of their NMR and MS data. Lycoplatyrine A (1) represents an unusual lycodine-piperidine adduct. The structures and absolute configurations of lycoplanine D (hydroxy-des-N-methyl-α-obscurine, 10) and lycogladine H (11) were confirmed by X-ray diffraction analysis. © 2019 American Chemical Society and American Society of Pharmacognosy.
Keywords
Alkaloids, Lycopodium, Club moss
Divisions
CHEMISTRY,InstituteofBiologicalSciences
Funders
University of Malaya (BK065-2014),MOE Malaysia (FRGS, FP041-2015A)
Publication Title
Journal of Natural Products
Volume
82
Issue
2
Publisher
American Chemical Society