Novel domino procedures for the synthesis of chromene derivatives and their isomerization
Document Type
Article
Publication Date
1-1-2016
Abstract
Novel tricyclic keto diesters have been synthesized by a one-pot three-component procedure via DABCO-catalyzed domino Knoevenagel–Michael addition reactions. Also, an efficient four-component reaction for the synthesis of another new group of tricyclic keto diesters has been developed via domino Knoevenagel-intramolecular oxo-Diels–Alder reactions. A selective thermal isomerization of the synthesized chromenes to fumarates is also described. X-ray analyses confirm unambiguously the structures of the products.
Keywords
Domino reaction, Michael addition, Oxo-Diels–Alder, Chromene, Isomerization, DABCO, Iminolactone, MCRs
Divisions
CHEMISTRY
Publication Title
Molecular Diversity
Volume
20
Issue
3
Publisher
Kluwer (now part of Springer)
COinS