Influence of degree of substitution on the host-guest inclusion complex between ionic liquid substituted β-cyclodextrins with 2,4-dichlorophenol: An electrochemical, NMR and molecular docking studies
Document Type
Article
Publication Date
1-1-2019
Abstract
A mono- and di-substituted ionic liquid-β-cyclodextrin (β-CD-ILs) were synthesized and their host-guest inclusion complex with 2, 4-dichlorophenol (2,4-DCP) were evaluated by electrochemical study. First, both β-CD-ILs which is β-CD-1-BIMOTs and β-CD-2-BIMOTs were fabricated on carbon paste electrode (CPE) for determination of 2,4-DCP. The cyclic voltammetry results indicate that both β-CD-IL/CPEs exhibit higher oxidation peak current compared to native β-CD/CPE. Both complexes possess high sensitivity, stability and reproducibility. However, as the degree of substitution of ionic liquid (IL) increases, the selectivity of β-CD-IL towards 2,4-DCP decreases. Thus, it can be deduced that the degree of substitution of IL is influencing the host-guest inclusion complex of β-CD-ILs with 2,4-DCP. © 2019 Elsevier B.V.
Keywords
Ionic liquid-β-cyclodextrin, 2, 4-dichlorophenol, Carbon paste electrode, Inclusion complex, NOESY analysis, Molecular docking
Divisions
CHEMISTRY
Funders
UMRG Projects ( RP020-16SUS and RP011B-14SUS ),PPP grant: PG050-2014B from University of Malaya,Ministry of Education Malaysia for My-Brain (My-PhD) scholarship given to a student named Fairuz Liyana Mohd Rasdi ( SHC140048 )
Publication Title
Journal of Molecular Liquids
Volume
292
Publisher
Elsevier