Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
Document Type
Article
Publication Date
1-1-2019
Abstract
The structure elucidation of three new alkaloids named isoformosaninol (1), formosaninol (2), and longiflorine (3), isolated from the leaves of Uncaria longiflora var. pteropoda (Miq.) Ridsdale, along with their biosynthetic pathways are discussed. Their absolute structures were determined through a combination of physical data interpretation and quantum chemical calculations using the time-dependent density functional theory (TDDFT) method. Copyright © 2019 American Chemical Society and American Society of Pharmacognosy.
Keywords
Uncaria, Cat's Claw, U tomentosa
Divisions
CHEMISTRY
Funders
Malaysian Government grant through the Fundamental Research Grant Scheme Fund, Grant 600-RMI/FRGS 5/3 (49/2013),Universiti Teknologi MARA through BESTARI Grant 5/3/BESTARI (0028/2016) and GIP Grant 600-IRMI-MYRA 5/3/GIP (088/2017)
Publication Title
Journal of Natural Products
Volume
82
Issue
11
Publisher
American Chemical Society