Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: an updated review

Document Type

Article

Publication Date

1-1-2018

Abstract

BODIPYs are photosensitizers activatable by light to generate highly reactive singlet oxygen (1O2) from molecular oxygen, leading to tissue damage in the photoirradiated region. Despite their extraordinary photophysical characteristics, they are not featured in clinical photodynamic therapy. This review discusses the recent advances in the design and/or modifications of BODIPYs since 2013, to improve their potential in photodynamic cancer therapy and related areas.

Keywords

Antineoplastic Agents, Boron Compounds, Humans, Neoplasms, Photochemotherapy, Photosensitizing Agents

Divisions

fac_med

Funders

Postgraduate Research Grant (PPP) – Research, project no. PG222-2016A

Publication Title

Photochemical & Photobiological Sciences

Volume

17

Issue

11

Publisher

Royal Society of Chemistry

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