Cycloartane Triterpenoids with Anti-melanin Deposition Activity

Document Type

Article

Publication Date

1-1-2018

Abstract

Bioactivity guided separation of the extract of Malaysian Garcinia sp. resulted in the isolation of 23-acetoxy-mangiferonic acid (1) and the absolute configuration of C-23 was elucidated to be R by the advanced Mosher's method. The anti-melanin deposition activity of 1 was caused by the down regulation of tyrosinase gene expression.

Keywords

Garcinia, Triterpenoids, Cycloartane, 23-Acetoxy-mangiferonic acid, Anti-melanin deposition activity

Divisions

CHEMISTRY

Publication Title

Natural Product Communications

Volume

13

Issue

7

Publisher

SAGE Publications

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