Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report

Document Type

Article

Publication Date

1-1-2017

Abstract

Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were positive, aided by computerized tomography-guided histological confirmation. Despite medical therapy, there was inadequate resolution, and surgical resection was performed. On follow-up, investigations showed complete resolution, and the patient has remained disease-free at 5 years. This highlights the importance of looking for other sites in resistant cryptococcal meningitis and the value of cardiothoracic intervention for slowly resolving pulmonary cryptococcomas.

Keywords

Cryptococcal meningitis, Disseminated, Immunocompetent host

Divisions

fac_med

Publication Title

Indian Journal of Thoracic and Cardiovascular Surgery

Volume

33

Issue

4

Publisher

Springer Verlag

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