Di-cationic Ionic Liquid Catalyzed Synthesis of 1,5-Benzothiazepines
Document Type
Article
Publication Date
1-1-2017
Abstract
A simple and elegant method for the synthesis of 1,5-benzothiazepines has been developed using di-cationic liquid as a solvent cum catalyst by the reaction of o-aminothiophenol with a variety of chalcones under mild reaction conditions. Furthermore the reusability of the catalyst has also been studied for three cycles. All the reactions are proposed to proceed through a 1,4-conjugate Michael addition followed by a cyclo-condensation reaction.
Keywords
gem-Dicationic ionic liquids, 1, 5-Benzothiazepines, 1, 5-Benzodiazepines, Cyclo-condensation reaction, Reusability
Divisions
CHEMISTRY,GEOLOGY
Funders
University of Malaya: research fellowships,Malaysian Ministry of Science, Technology and Innovation (MOSTI) through IPharm for the grant No. 53-02-03-1059
Publication Title
Asian Journal of Chemistry
Volume
30
Issue
1
Publisher
Chemic Publishing Company