tert-Butyl 2-{[2,8-bis(trifluoromethyl)-quinolin-4-yl](hydroxy)methyl}-piperidi ne-1-carboxylate

Document Type

Article

Publication Date

1-1-2011

Abstract

The title molecule, C22H24F6N2O3, adopts a folded conformation whereby the carboxylate residue lies over the quinolinyl residue, with the dihedral angle between the carbamate and quinoline planes being 41.64 (7)degrees. Helical supramolecular C(7) chains sustained by O-H center dot center dot center dot O hydrogen bonds propagating along the a-axis direction feature in the crystal packing. The F atoms of one of the CF3 groups are disordered over two orientations; the major component has a site occupancy of 0.824 (7).

Publication Title

Acta Crystallographica Section E: Structure Reports Online

Volume

67

Issue

12

Publisher

International Union of Crystallography

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