Document Type
Article
Publication Date
1-1-2015
Abstract
From food to fertilizer, algal derived products are largely employed in assorted industries, including agricultural, biomedical, food, and pharmaceutical industries. Among different chemical compositions isolated from algae, polysaccharides are the most well-established compounds, which were subjected to a variety of studies due to extensive bioactivities. Over the past few decades, the promising results for antiviral potential of algae-derived polysaccharides have advocated them as inordinate candidates for pharmaceutical research. Numerous studies have isolated various algal polysaccharides possessing antiviral activities, including carrageenan, alginate, fucan, laminaran, and naviculan. In addition, different mechanisms of action have been reported for these polysaccharides, such as inhibiting the binding or internalization of virus into the host cells or suppressing DNA replication and protein synthesis. This review strives for compiling previous antiviral studies of algae-derived polysaccharides and their mechanism of action towards their development as natural antiviral agents for future investigations.
Keywords
Antiviral Potential, Algae Polysaccharides, Marine Sources
Divisions
fac_med
Funders
Ministry of Higher Education (MOHE), Malaysia. Fundamental Research Grant Scheme (FRGS) (FP054-2014B) and Long-Range Grant Scheme (LRGS) LR001/2011F,University of Malaya. University Malaya Flagship Grant (UMRG) (FL001-13HTM)
Publication Title
BioMed Research International
Volume
2015
Publisher
Hindawi Publishing Corporation