Document Type
Article
Publication Date
1-1-2014
Abstract
The present study was conducted to fabricate a 3D scaffold using polycaprolactone (PCL) and silicate based bioactive glass-ceramic (R-SBgC). Different concentrations of R-SBgC prepared from rice husk ash (RHA) were combined with PCL to fabricate a composite scaffold using thermally induced phase separation (TIPS) method. The products were then characterized using SEM and EDX. The results demonstrated that R-SBgC in PCL matrix produced a bioactive material which has highly porous structure with interconnected porosities. There appears to be a relationship between the increase in R-SBgC concentration and increased material density and compressive modulus; however, increasing R-SBgC concentration result in reduced scaffold porosity. In conclusion, it is possible to fabricate a PCL/bioactive glass-ceramic composite from processed rice husk. Varying the R-SBgC concentrations can control the properties of this material, which is useful in the development of the ideal scaffold intended for use as a bone substitute in nonload bearing sites.
Keywords
in-vitro characterization, mechanical-properties, calcium phosphates, graft substitutes, bone-graft, rice husk, silica, biomaterials, regeneration
Divisions
fac_med
Publication Title
Journal of Nanomaterials (JNM)
Volume
2014
Issue
2014
Publisher
Hindawi Publishing Corporation
Additional Information
ISI Document Delivery No.: 303HK Times Cited: 0 Cited Reference Count: 29 Naghizadeh, Farnaz Sultana, Naznin Kadir, Mohammed Rafiq Abdul Shihabudin, Tengku Muzaffar Tengku Md Hussain, Rafaqat Kamarul, Tunku Universiti Teknologi Malaysia (UTM); Research Management Center (RMC); Ministry of Higher Education (MOHE); Faculty of Bioscience and Medical Engineering (FBME); UTM research Grants 79412, 4F126, 03H13; University of Malaya HIR-MOHE research grant initiative The authors acknowledge the Universiti Teknologi Malaysia (UTM), the Research Management Center (RMC), the Ministry of Higher Education (MOHE), and the Faculty of Bioscience and Medical Engineering (FBME). This research was supported by UTM research Grants (vote: 79412 and 4F126, 03H13). One of the authors of this paper is supported by the University of Malaya HIR-MOHE research grant initiative. Hindawi publishing corporation New york