In-vitro screening of antifungal activity of plants in Malaysia
Document Type
Article
Publication Date
1-1-2011
Abstract
Twelve species of local Malaysian plants and 5 strains of medically important fungi were se-lected for this study. Antifungal susceptibility test was performed to screen the antifungal activity of these plants against the selected fungi. Piper betel produced the best result in anti-fungal susceptibility testing and showed to possess antifungal property against 4 out of 5 strains of the fungus. Solid Phase extraction (SPE) technique was applied to Piper betel to achieve initial separation of active antifungal compound in the form of methanol fractions. These fractions were tested for their antifungal property. Piper betel showed the best anti-fungal activity especially against Trichophyton rubrum.
Keywords
In-vitro screening, Antifungal activity, Malaysian plants, Solid phase extraction, Piper betel
Divisions
Science
Publication Title
Biomedical Research
Volume
22
Issue
1
Publisher
Biomedical Research Press