Fragment-based molecular design of new competitive dengue den2 ns2b/ns3 inhibitors from the components of fingerroot(Boesenbergia Rotunda)
Document Type
Article
Publication Date
1-1-2011
Keywords
Boesenbergia rotunda, Dengue DEN2 NS2B/NS3, Docking, Fragment-based, chalcone derivative, ligand, NS3 protease, dengue virus, panduratin A, serine proteinase, serine proteinase inhibitor, virus protein, article, chemical phenomena, chemical structure, chemistry, dengue, Dengue virus, drug antagonism, drug design, drug effect, enzyme active site, genetics, hydrogen bond, Zingiberaceae, Catalytic Domain, Chalcones, Hydrogen Bonding, Hydrophobic and Hydrophilic Interactions, Ligands, Models, Molecular, Serine Endopeptidases, Serine Proteinase Inhibitors, Viral Nonstructural Proteins
Divisions
CHEMISTRY
Publication Title
In Silico Biology
Volume
11
Issue
1-2
Additional Information
Department of Chemistry, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
COinS