Alternative animal model for Pasteurella multocida and Haemorrhagic septicaemia
Document Type
Article
Publication Date
1-1-2013
Abstract
A suitable animal model is essential in understanding a condition caused by microorganisms. In this study in order to study the changes in haemorrahgic septicaemia caused by Pasteurella multocida serotype B, Sprague-Dawley (SK/WDY) rats were immuo-suppressed with dexamethasone and challenged with P.multocida serotype B:2. The animals were monitored/inspected twice daily. Any changes in behaviour, movement, eating and development of any signs and symptoms were recorded. Immune-suppressed rats showed signs of haemorrahge and lesion in the lungs.
Keywords
Pasteurella multocida, Haemorrhagic septicaemia, Animal model
Divisions
Science
Publication Title
Biomedical Research
Volume
24
Issue
2
Publisher
Biomedical Research Press