Document Type
Article (Restricted)
Publication Date
1-1-2012
Abstract
Malaria is still a public health problem in Malaysia with chloroquine (CQ) being the first-line drug in the treatment policy of uncomplicated malaria. There is a scarcity in information about the magnitude of Plasmodium falciparum CQ resistance. This study aims to investigate the presence of single point mutations in the P. falciparum chloroquine-resistance transporter gene (pfcrt) at codons 76, 271, 326, 356 and 371 and in P. falciparum multi-drug resistance-1 gene (pfmdr1) at codons 86 and 1246, as molecular markers of CQ resistance
Keywords
Malaria, Plasmodium falciparum, P. falciparum
Divisions
fac_med
Publication Title
Malaria Journal
Publisher
BioMed Central
COinS