Regioselective synthesis of 3,5-diaryl-4-methylisoxazoles

Document Type

Article

Publication Date

1-1-2012

Abstract

Abstract: A new class of isoxazole derivatives, namely 2-(3-aryl-4-methylisoxazol-5-yl)phenols, has been efficiently synthesized through the regioselective reaction of 2-aryl-3-methylchromones with hydroxylamine. The products were characterized by spectroscopic methods and X-ray crystallography. Graphical Abstract: [Figure not available: see fulltext.]. © 2012 Springer-Verlag.

Keywords

2-(3-Aryl-4-methylisoxazol-5-yl)phenols, 2-Aryl-3-methyl-4 H-chromen-4-ones, Hydroxylamine hydrochloride, Regioselectivity

Divisions

CHEMISTRY

Publication Title

Monatshefte fur Chemie

Additional Information

Department of Chemistry, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA

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