Insights from the genome sequence of a salmonella enterica serovar typhi strain associated with a sporadic case of typhoid fever in Malaysia

Authors

K.P. Yap
C.S.J. Teh
R. Baddam
L.C. Chai
N. Kumar
T.S. Avasthi
N. Ahmed
Kwai Lin ThongFollow

Document Type

Article

Publication Date

1-1-2012

Abstract

Salmonella enterica serovar Typhi is the causative agent of typhoid fever, which causes nearly 21.7 million illnesses and 217,000 deaths globally. Herein, we describe the whole-genome sequence of the Salmonella Typhi strain ST0208, isolated from a sporadic case of typhoid fever in Kuala Lumpur, Malaysia. The whole-genome sequence and comparative genomics allow an in-depth understanding of the genetic diversity, and its link to pathogenicity and evolutionary dynamics, of this highly clonal pathogen that is endemic to Malaysia.

Keywords

Field Gel-Electrophoresis, Rast Server, Rna Genes, Annotation, Resistance, Vietnam, DNA

Divisions

InstituteofBiologicalSciences

Publication Title

Journal of Bacteriology

Volume

194

Issue

18