Cardiovascular risk scores do not account for the effect of treatment: a review.
Document Type
Article
Publication Date
5-1-2011
Abstract
The use of risk-factor-modifying drugs-for example, statins-and disease-modifying medication-for example, platelet inhibitors-was not accounted for. In addition, none of the risk scores addressed the effect of treatment drop-ins-that is, treatment started during the study period. Ideally, a risk score should be derived from a population free from treatment. The lack of accounting for treatment effect and the wide variation in study characteristics, predictors and outcomes causes difficulties in the use of cardiovascular risk scores for clinical treatment decision.
Keywords
Adult, Aged, Cardiovascular Agents/therapeutic use
Publication Title
Heart (British Cardiac Society)
Volume
97
Issue
9
Additional Information
Department of Primary Care Medicine and Julius Center UM,University of Malaya, KualaLumpur, Malaysia.