Benzyl 2-{[2,8-bis(trifluoromethyl)-quinolin-4-yl](hydroxy)methyl}-piperidi ne-1-carboxylate

Authors

M.V.N. de Souza
R.S.B. Goncalves
J.L. Wardell
S.M.S.V. Wardell
E.R.T. Tiekink

Document Type

Article

Publication Date

1-1-2011

Abstract

The title molecule, C(25)H(22)F(6)N(2)O(3), adopts an open conformation whereby the quinoline and carboxylate ester groups are orientated in opposite directions but to the same side of the piperidine ring so that the molecule has an approximate U-shape. The piperidine ring adopts a distorted boat conformation. In the crystal, inversion dimers linked by pairs of O-H center dot center dot center dot O hydrogen bonds generate R(2)(2)(14) loops.

Publication Title

Acta Crystallographica Section E: Structure Reports Online

Volume

67

Issue

12

Publisher

International Union of Crystallography