Chronic neutrophilic leukaemia.
Document Type
Article
Publication Date
3-1-2007
Abstract
Chronic neutrophilic leukaemia is a rare myeloproliferative disease characterised by splenomegaly, sustained neutrophilia, raised vitamin B12 level and absence of the Philadelphia chromosome. We report a 74-year-old man who presented first with Sweet's syndrome and subsequently leukocytosis. He had splenomegaly, a raised vitamin B12 level, serum uric acid and neutrophil alkaline phosphatase score. Cytogenetic study of the marrow was normal and peripheral blood for BCR-ABL gene transcript was not detectable. He subsequently passed away with bronchopneumonia.
Keywords
Aged, Angiogenesis Inhibitors/therapeutic use, Fatal Outcome
Divisions
fac_med
Publication Title
Singapore Medical Journal
Volume
48
Issue
3
Publisher
Stamford Publishing Pte Ltd / Singapore Medical Association
COinS