ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis.

Authors

• B.S. Haerian
• H. Roslan
• A.A. Raymond
• C.T. Tan
• K.S. Lim
• S.Z. Zulkifli
• E.H.M. Mohamed
• H.J. Tan
• Z. Mohamed

Document Type

Article

Publication Date

7-1-2010

Abstract

We failed to show an association between the ABCB1 C3435T polymorphism and the risk of drug-resistance suggesting a revision in contribution of this polymorphism in the multi-drug transporters hypothesis of pharmacoresistance to AEDs in epilepsy.

Keywords

Anticonvulsants/therapeutic use, Data Interpretation, Statistical

Publication Title

Seizure : the journal of the British Epilepsy Association

ISSN

1532-2688

Recommended Citation

Haerian, B.S.; Roslan, H.; Raymond, A.A.; Tan, C.T.; Lim, K.S.; Zulkifli, S.Z.; Mohamed, E.H.M.; Tan, H.J.; and Mohamed, Z., "ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis." (2010). Research Publications (2006 to 2010). 4748.
https://knova.um.edu.my/research_publications_2006_2010/4748

Divisions

fac_med

Volume

19

Issue

6

Additional Information

Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. batoolsadat@yahoo.com