Document Type
Article
Publication Date
1-1-2010
Abstract
The haemoglobinopathies and thalassemias represent the most common inherited monogenic disorders in the world. Beta-thalassaemia major is an ongoing public health problem in Malaysia. Prior to 2004, the country had no national policy for screening and registry for thalassemia. In the absence of a national audit, the true figure of the extent of thalassemia in the Malaysian population was largely presumptive from micro-mapping studies from various research workers in the country. The estimated carrier rate for beta-thalassemia in Malaysia is 3.5-4. There were 4768 transfusion dependent thalassemia major patients as of May 2010 (Data from National Thalassemia Registry).
Keywords
Genotype-phenotype thalassemia Malaysia treatment options
Publication Title
Medical Journal of Malaysia
ISSN
0300-5283
Recommended Citation
Elizabeth, G. and Ann, T.J.A.M., "Genotype-Phenotype diversity of Beta-Thalassemia in Malaysia: treatment options and emerging therapies" (2010). Research Publications (2006 to 2010). 4402.
https://knova.um.edu.my/research_publications_2006_2010/4402
Divisions
fac_med
Volume
65
Issue
4
Publisher
Malaysian Medical Association
Additional Information
Department of Molecular Medicine, Faculty of Medicine, Unieversity of Malaya, 50603, Kuala Lumpur