Document Type
Article
Publication Date
1-1-2010
Abstract
Mannose-binding lectin from champedak (Artocarpus integer) is a homotetramer with a single-monomer molecular weight of 16 800 Da. Previous work has shown it to bind IgE and IgM, as well as being a mitogen of T cells in humans. Champedak mannose-binding lectin has successfully been used to detect altered glycosylation states of serum proteins. The protein was crystallized at 293 K in space group P2(1)2(1)2(1) (unit-cell parameters a = 76.89, b = 86.22, c = 95.37 angstrom) and the crystals diffracted to 2.0 angstrom resolution.
Keywords
lectins, Artocarpus integer, champedak, mannose binding.
Divisions
fac_med
Publication Title
Acta Crystallographica Section F-Structural Biology and Crystallization Communications
Volume
66
Issue
5
Additional Information
Gabrielsen, Mads Abdul-Rahman, Puteri Shafinaz Isaacs, Neil W. Hashim, Onn Haji Cogdell, Richard J. Part 5