Progressive multifocal leukoencephalopathy limited to the posterior fossa

Document Type

Article

Publication Date

1-1-2010

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive demyelinating disease caused by the reactivation of JC papova virus usually in immunocompromised hosts.(1) The disease is a chronic viral infection resulting in mortality within a year.(2) The condition characterized by white matter changes in multiple locations of the brain is caused by destruction of the oligodendrogliocytes.(2) We report a case of AIDS associated PML presenting with progressive cerebellar symptoms, with the unusual feature of imaging abnormalities limited to the posterior fossa.

Publication Title

Neurology Asia

Volume

15

Issue

3

Publisher Location

UNIV MALAYA MEDICAL CENTRE, NEUROLOGY LABORATORY, KUALA LUMPUR, 59100, MALAYSIA

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