Progressive multifocal leukoencephalopathy limited to the posterior fossa

Authors

• K. Rahmat
• S. Kaur
• N.M. Ramli
• P.A. Chandran
• Kum Thong WongFollow
• S. Abdullah
• S.S. Omar
• D. Ganesan
• Chong Tin TanFollow

Document Type

Article

Publication Date

1-1-2010

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive demyelinating disease caused by the reactivation of JC papova virus usually in immunocompromised hosts.(1) The disease is a chronic viral infection resulting in mortality within a year.(2) The condition characterized by white matter changes in multiple locations of the brain is caused by destruction of the oligodendrogliocytes.(2) We report a case of AIDS associated PML presenting with progressive cerebellar symptoms, with the unusual feature of imaging abnormalities limited to the posterior fossa.

Publication Title

Neurology Asia

ISSN

1823-6138

Recommended Citation

Rahmat, K.; Kaur, S.; Ramli, N.M.; Chandran, P.A.; Wong, Kum Thong; Abdullah, S.; Omar, S.S.; Ganesan, D.; and Tan, Chong Tin, "Progressive multifocal leukoencephalopathy limited to the posterior fossa" (2010). Research Publications (2006 to 2010). 3939.
https://knova.um.edu.my/research_publications_2006_2010/3939

Volume

15

Issue

3

Publisher Location

UNIV MALAYA MEDICAL CENTRE, NEUROLOGY LABORATORY, KUALA LUMPUR, 59100, MALAYSIA