Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis.

Document Type

Article

Publication Date

1-1-2010

Abstract

Phyllanthus plant exerts its growth inhibition effect in a selective manner towards cancer cells through the modulation of cell cycle and induction of apoptosis via caspases activation in melanoma and prostate cancer cells. Hence, Phyllanthus may be sourced for the development of a potent apoptosis-inducing anticancer agent.

Keywords

Antineoplastic Agents, Phytogenic/pharmacology, Apoptosis/drug effects

Divisions

fac_med

Publication Title

PLoS ONE

Volume

5

Issue

9

Publisher

Public Library of Science

Additional Information

Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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