Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis.

Authors

• Y. Tang
• I.B. Jaganath
• S.D. Sekaran

Document Type

Article

Publication Date

1-1-2010

Abstract

Phyllanthus plant exerts its growth inhibition effect in a selective manner towards cancer cells through the modulation of cell cycle and induction of apoptosis via caspases activation in melanoma and prostate cancer cells. Hence, Phyllanthus may be sourced for the development of a potent apoptosis-inducing anticancer agent.

Keywords

Antineoplastic Agents, Phytogenic/pharmacology, Apoptosis/drug effects

Publication Title

PLoS ONE

ISSN

1932-6203

Recommended Citation

Tang, Y.; Jaganath, I.B.; and Sekaran, S.D., "Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis." (2010). Research Publications (2006 to 2010). 3896.
https://knova.um.edu.my/research_publications_2006_2010/3896

Divisions

fac_med

Volume

5

Issue

9

Publisher

Public Library of Science

Additional Information

Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia