Ethyl 2-{4-[(1,5-dibenzyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin -3-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate

Authors

• H. Jabli
• Y.K. Rodi
• S. Ladeira
• E.M. Essassi
• S.W. Ng

Document Type

Article

Publication Date

1-1-2010

Abstract

The reaction of 1,5-dibenzyl-3-propargyl-1,5-benzodiazepine-2,4-dione with ethyl azidoacetate in the presence of copper sulfate pentahydrate and sodium ascorbate leads to the formation of the title regioisomer, C(30)H(29)N(5)O(4), which features a phenylene ring fused with a seven-membered diazepinyl ring. The latter ring adopts a boat conformation (with the methyltriazolylacetate-bearing C atom as the prow and the fused-ring C atoms as the stern). The benzyl groups connected to the diazepinyl ring jprotrude from the sides; the methyltriazolylacetate substituent occupies an axial position.

Publication Title

Acta Crystallographica Section E: Structure Reports Online

ISSN

1600-5368

Recommended Citation

Jabli, H.; Rodi, Y.K.; Ladeira, S.; Essassi, E.M.; and Ng, S.W., "Ethyl 2-{4-[(1,5-dibenzyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin -3-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate" (2010). Research Publications (2006 to 2010). 3489.
https://knova.um.edu.my/research_publications_2006_2010/3489

Volume

66

Issue

1

Publisher

International Union of Crystallography

Publisher Location

COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA