Ethyl 2-{4-[(1,5-dibenzyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin -3-yl)methyl]-1H-1,2,3-triazol-1-yl}acetate
Document Type
Article
Publication Date
1-1-2010
Abstract
The reaction of 1,5-dibenzyl-3-propargyl-1,5-benzodiazepine-2,4-dione with ethyl azidoacetate in the presence of copper sulfate pentahydrate and sodium ascorbate leads to the formation of the title regioisomer, C(30)H(29)N(5)O(4), which features a phenylene ring fused with a seven-membered diazepinyl ring. The latter ring adopts a boat conformation (with the methyltriazolylacetate-bearing C atom as the prow and the fused-ring C atoms as the stern). The benzyl groups connected to the diazepinyl ring jprotrude from the sides; the methyltriazolylacetate substituent occupies an axial position.
Publication Title
Acta Crystallographica Section E: Structure Reports Online
Volume
66
Issue
1
Publisher
International Union of Crystallography
Publisher Location
COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA