Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis

Authors

• Chew Yan Gan
• Yun Yee LowFollow
• W.T. Robinson
• K. Komiyama
• Toh Seok KamFollow

Document Type

Article

Publication Date

1-1-2010

Abstract

Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells. (C) 2010 Elsevier Ltd. All rights reserved.

Keywords

Bisindole alkaloids, Leuconotis, NMR, X-ray, Cytotoxicity

Publication Title

Phytochemistry

ISSN

0031-9422

Recommended Citation

Gan, Chew Yan; Low, Yun Yee; Robinson, W.T.; Komiyama, K.; and Kam, Toh Seok, "Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis" (2010). Research Publications (2006 to 2010). 3123.
https://knova.um.edu.my/research_publications_2006_2010/3123

Volume

71

Issue

11-12

Publisher

Elsevier

Publisher Location

THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND