Nephrotic Syndrome in a Patient with Relapsed of Chronic Myeloid Leukemia after Peripheral Blood Stem Cell Transplantation
Document Type
Article
Publication Date
3-1-2008
Abstract
Nephrotic syndrome (NS) is a well documented complication after allogeneic peripheral blood stem cell transplantation. It is usually due to autoimmune glomerulonephritis and thought to be a clinical manifestation of graft versus host disease. NS has also been reported to be associated with other hematological malignancies. We report a case of nephrotic syndrome in a patient who relapsed after allogeneic peripheral blood stem cell transplantation (PBSCT) for chronic myeloid leukemia (CML). The renal biopsy was suggestive of minimal change disease. There was no other evidence of graft versus host disease. He was treated with high dose prednisolone, with no response and finally succumbed to the underlying disease.
Keywords
Nephrotic syndrome, GVHD, PBSCT, Chronic myeloid leukemia
Divisions
fac_med
Publication Title
Medical Journal of Malaysia
Volume
63
Issue
1
Publisher
Malaysian Medical Association