Document Type
Article (Restricted)
Publication Date
1-1-2008
Abstract
In this study, we analysed the genetic polymorphisms present in the third intron region of Interleukin-4 gene in Malaysian patients with Systemic Lupus Erythematosus. Overall, the RP I and II alleles were found evenly distributed in both the SLE patients and control individuals. There was no significant association observed in the distribution of allelic and genotypic frequencies between SLE patients and healthy controls. The result obtained is similar to a previous study carried out on SLE Chinese patients in Taiwan.
Keywords
Interleukin-4, systemic lupus erythematosus, genetic polymorphisms, third intron, variable number of tandem repeat
Publication Title
Journal of Medical Sciences
ISSN
1682-4474
Recommended Citation
Chua, K.H.; Pin, K.B.; Yen, T.S.; and Hoong, L.L., "Genetic polymorphisms of interleukin-4 third intron region in the Malaysian patients with systemic lupus erythematosus" (2008). Research Publications (2006 to 2010). 1468.
https://knova.um.edu.my/research_publications_2006_2010/1468
Divisions
fac_med
Volume
8
Issue
4
Publisher
Asian Network for Scientific Information
Additional Information
Department of Molecular Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA