Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.

Authors

• Khalijah AwangFollow
• Kartini AhmadFollow
• Noel Francis ThomasFollow
• Yusuke Hirasawa
• Koichi Takeya
• Mat Ropi MukhtarFollow
• Khalit Mohamad
• Hiroshi Morita

Document Type

Article

Publication Date

1-1-2008

Abstract

Study on chemical constituents from the leaves of Kopsia singapurensis (Apocynaceae) yielded a new indole alkaloid, singaporentine A (1) together with two known alkaloids, kopsifoline A (2) and kopsininic acid (3). The structure of 1 was elucidated by combination of various spectroscopic methods such as MS, UV, IR, ID and 2D NMR. Singaporentine A exhibited cytotoxic activity against P388 murine leukemia cells. © 2008 The Japan Institute of Heterocyclic Chemistry.

Keywords

Melodinus, Tabernaemontana, Rauwolfia Alkaloid

Publication Title

Heterocycles

ISSN

0385-5414

Recommended Citation

Awang, Khalijah; Ahmad, Kartini; Thomas, Noel Francis; Hirasawa, Yusuke; Takeya, Koichi; Mukhtar, Mat Ropi; Mohamad, Khalit; and Morita, Hiroshi, "Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl." (2008). Research Publications (2006 to 2010). 1210.
https://knova.um.edu.my/research_publications_2006_2010/1210

Divisions

fac_med,CHEMISTRY

Volume

75

Issue

12

Publisher

The Japan Institute of Heterocyclic Chemistry