Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.

Document Type

Article

Publication Date

1-1-2008

Abstract

Study on chemical constituents from the leaves of Kopsia singapurensis (Apocynaceae) yielded a new indole alkaloid, singaporentine A (1) together with two known alkaloids, kopsifoline A (2) and kopsininic acid (3). The structure of 1 was elucidated by combination of various spectroscopic methods such as MS, UV, IR, ID and 2D NMR. Singaporentine A exhibited cytotoxic activity against P388 murine leukemia cells. © 2008 The Japan Institute of Heterocyclic Chemistry.

Keywords

Melodinus, Tabernaemontana, Rauwolfia Alkaloid

Divisions

fac_med,CHEMISTRY

Publication Title

Heterocycles

Volume

75

Issue

12

Publisher

The Japan Institute of Heterocyclic Chemistry

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