Determination of pKa of ammonium and phenolic groups: Evidence of intramolecular hydrogen bonding in aqueous solution

Document Type

Article

Publication Date

1-1-2008

Abstract

The ionization constants of 2-hydroxyanilinium, 2-methoxyanilinium, 4-nitroanilinium ions, N-(2′-hydroxyphenyl)-phthalamic acid and N-(2′-methoxyphenyl) phthalamic acid, determined spectrophotometrically, have been rationalized in terms of internal hydrogen bonding and steric hindrance between o-substituent and reaction site.

Keywords

ionization, 2-hydroxyanilinium, 2-methoxyanilinium, 4-nitroanilinium ions, N-(2′-hydroxyphenyl)-phthalamic acid, N-(2′-methoxyphenyl) phthalamic acid, spectrophotometrically, internal hydrogen bonding, steric hindrance, o-substituent, reaction site.

Divisions

CHEMISTRY

Publication Title

Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry

Volume

47

Issue

2

Additional Information

Department of Chemistry, Faculty of Science Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA

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