Document Type
Article (Restricted)
Publication Date
1-1-2004
Abstract
In this immunohistochemical examination, the expression of Notch1 peptide was detected in neoplastic cells in a case of osteosarcoma of the maxilla of a 31-year-old Indonesian male patient. Notch1 peptide appeared in the cytoplasm of neoplastic cells of comparatively well-differentiated areas of the osteosarcoma, an osteoblastic area containing osteoid and/or immature bone tissues. The results suggest that Notch1 is closely related to cytological differentiation or acquisition of cytological characteristics in neoplastic cells of osteosarcoma.
Keywords
Osteosarcoma Notch1 peptide cytological characteristics morphogenesis cyto-differentiation morphogenesis regulation factor immunohistochemistry osteoblastic cells differentiation
Divisions
OralPathologyOralMedicinePeriodontology
Publication Title
European Journal of Medical Research
Volume
9
Issue
11
Additional Information
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