Localised nodular pulmonary amyloidosis in a patient with sicca syndrome
Document Type
Article
Publication Date
1-1-2000
Abstract
A 52 year old Chinese woman with a 25 year history of sicca syndrome (primary Sjogrens syndrome) was investigated for 3 episodes of haemoptysis. Clinical examination was unremarkable except for the presence of dry eyes and xerostomia. Computed tomography of the chest revealed a lobulated mass in the posterior basal segment of the left lower lobe. Histopathological examination of this resected nodule confirmed the diagnosis of nodular amyloidosis. The normal radiolabelled serum amyloid P component scintigraphy and the absence of monoclonal plasma cell dyscrasia in the bone marrow strongly support the diagnosis of localised nodular pulmonary AL amyloidosis in this patient. Nodular pulmonary amyloidosis can be associated with sicca syndrome and often simulates bronchogenic carcinoma, bronchiectasis or pulmonary tuberculosis.
Keywords
Amyloidosis, Female, Humans, Lung Diseases, Middle Aged, Sjogren's Syndrome, Tomography, X-Ray Computed
Divisions
fac_med
Publication Title
Medical Journal of Malaysia
Volume
55
Issue
3
Publisher
Malaysian Medical Association