Virucidal activity of Virkon S on human enterovirus
Document Type
Article
Publication Date
1-1-2005
Abstract
The efficacy of Virkon S, a commercial disinfectant as a virucidal spray against human enterovirus 71 (HEV71), the causative agent of the fatal form of hand, foot and mouth disease was examined. At least one log10 reduction of HEV71 titer was achieved when one spray of Virkon (1 or 2) with ten minutes of contact time was applied. The infectivity was completely lost when four sprays of 1 or 2 Virkon were applied, suggesting that at least four sprays of 1 Virkon to the surface bound HEV71 was necessary to completely inactivate the virus. These findings suggest that Virkon S at the proper concentration is suitable to be used as an effective and easy to use disinfectant against HEV71.
Keywords
Administration, Topical Disinfectants/administration & dosage/*therapeutic use Enterovirus/*classification/*drug effects Enterovirus Infections/*drug therapy/virology Humans Peroxides/administration & dosage/*therapeutic use Sulfuric Acids/administration & dosage/*therapeutic use Treatment Outcome
Divisions
fac_med
Publication Title
Medical Journal of Malaysia
Volume
60
Issue
2
Publisher
Malaysian Medical Association
Additional Information
Department of Medical Microbiology, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA